I discovered this animated image: http://gfycat.com/SoftDesertedAyeaye
What anime is this from? In an attempt to avoid including animated images, here is a still-shot from it.
In the animation, the character runs from 2 guys, but gets cornered. At this time, the hand appears to act on it's own, transforming into tools to subdue the pursuers.
I've tried Google's search by image tool, but no help. I'm also not sure what "Soft Deserted Ayeaye" would mean, but searching it brings up some creepy animal pictures.