The oldest animation, which originated from Japan, wasanime I found after some research is Astro boyBoy. It originated from Japan and started airing in the US on September 7, 1963. This is two months after Calimero, but Astro Boy is of Japanese origin, which Calimero is not.
I first looked through the wikipedia page on History of anime and the first title, "Astro Boy" looked familiar. Therefore I started reading through the page and there it said
The manga was adapted into the first popular animated Japanese television series that embodied the aesthetic that later became familiar worldwide as anime.
This was again repeated on the wiki page on the 1963 TV series
After enjoying success both in Japan and abroad as the first anime to be broadcast overseas, Astro Boy was remade in the 1980s under the same name(s), and in 2003 as Astro Boy: Mighty Atom
First I clicked the 1959 TV series, which at that time was still called "Mighty Atom", but later changed to "Astro Boy". The 1959 series didn't seem to have been broadcasted abroad though. It was only from the 1963 TV series, that the name was changed to Astro Boy, after discussions between producer Fred Ladd and representatives from NBC. The first United States broadcast was on September 7, 1963, which was only 9 months after the first release on New Year's day in Japan. More on the episode list with respective release dates for both Japan and the US can be found here