I read a lot of the Full Moon wo Sagashite manga a few years ago and recently started watching the anime. It's been so long since I read the manga that I can't tell how much is different, but I remember my friend telling me a few years ago that they are very different.
Is there a lot of filler in the anime? Is the plot/story significantly different?
Please mark any spoilers as corresponding to either the manga or anime so those who have only seen one or the other don't get spoiled if they don't want to.
(If my friend was blatantly wrong and they are pretty darn close, I apologize and don't mind having the question closed.)