I have been seeing this meme all over the internet. Guessing from most of the Q&As I have found, this seems to be edited in. If so, what was the original verse and why did it get twisted in this way?
At about 21:00 in Season 2 Episode 20, there's the same scene:
On the platform of the Sword of Akasha in the World of C, Charles zi Britannia is looking at the pillar-like object, telling the god that it's the time to finish everything. Lelouch then walks in saying that Charles is wrong.
I don't think the sub is related to the plot, but there may be one explanation:
"Not this shit again" might be one of Charles' inner thoughts when Lelouch walks in and interrupts him.