As we know, the Japanese have smaller eyes than western people, apparently as the result of an evolutionary adaptation against snow-blindness. But in anime, the Japanese draw everyone with big eyes. If an American cartoon were to draw a character with small eyes, it probably would mean they're Japanese, Korean, Chinese, etc. Though sometimes, anime have characters with small eyes.
What does it mean for them? Does it mean the character is from a specific area, or that they're old?