I know the details of those eyes, I know their combination gives birth to the Eternal Mangekyo Sharingan. When Madara was almost blind Izuna gave him his eyes, the same thing happened with Itachi and Sasuke.
In these two cases we've seen the Eternal Mangekyo Sharingan and here comes my question:
In the first case, Madara was "blind" and Izuna had the good eyes, the combination was the Eternal. In the second case, Itachi was "blind" and Sasuke had the full eyes, giving birth to the Eternal. So it's indifferent which eye it's transplanted in the host body? (It doesn't matter that the good eye gets a disadvantaged blind eye?)
As for the main question, how it is realized the "fusion" of 2 different eyes in one eye hole? I don't want to dig myself into the nerve/artery things. I'm interested more likely in the fact that how you mix 2 eyes into one and how the full eye and the blind eye, it's yet so much stronger??